Welcome to a new era of Regenerative Injectables - Polynucleotides

  • What are they?

    PNs are highly purified DNA molecules of natural extraction.

    Using highly purified Polynucleotides with clinically proven results, this product stimulates collagen and improves bio-regeneration of the skin.

  • How do Polynucleotides work?

    They are injected into the skin where they reach and stimulate production of fibroblasts. These support connective tissue and collagen which keeps the skin firm.

  • What product do we use at Skinphinity?

    At our Skinphinity clinics in Tarporley and Middlewich we use the Plinest range of Polynucleotides by Mastelli - a brand that has been established in Italy for 30 years.


How many treatments are needed?

For best results we recommend 3-4 treatments spaced 3 weeks apart.

What is the cost?

One treatment alone is £300 but this is not recommended in isolation.

Three treatments paid upfront are £800.

Four treatments are £900.

Can it be used alongside other treatments?

Absolutely! PNs are used as Skin Primers, meaning it can prepare the skin and make it more receptive to treatments like dermal fillers, microneedling, Botox, or even before surgery.

It can also be used alongside Profhilo - it isn't necessarily a replacement for this as it works very differently.